Arts and Humanities

• Ismail al-Faruqi, philosopher and epistemologist
• David Chalmers, leading philosopher in the area of philosophy of mind
• Robert Coover, author
• John Crowley, science-fiction author, author of The Deep and Little, Big
• Michel DuCille, photographer, two-time winner of the Pulitzer Prize
• Dick Enberg, sportscaster, 13-time Emmy Award winner
• Kevin Kline, actor
• Ross Lockridge, Jr., author of Raintree County
• Don Mellett, jounalist, newspaper editor, Pulitzer Price winner
• Jane Pauley, broadcaster
• Ernie Pyle, journalist
• Will Shortz, puzzle maker (enigmatologist)
• Clark Wissler, anthropology pioneer

Business

• Joe Barnette, retired chairman and CEO of Bank One
• John Chambers, president and CEO of Cisco Systems
• Mark Cuban, technology entrepreneur, Dallas Mavericks owner
• Katherine Hudson, president & CEO of Brady Corporation
• Frank Popoff, retired chairman and CEO of Dow Chemical Company
• Maggy Siegel, president & CEO, Judith Leiber LLC
• Fred Steingraber, chairman and CEO of consulting company AT Kearney
• Corey Torrence, president and CEO of marketing company Epsilon
• Todd Wagner, CEO of 2929 Entertainment; Founder of Todd Wagner Foundation; Co-Founder of Broadcast.com
• Jimbo Wales, CEO of Bomis, founder of Wikipedia, president of the Wikimedia Foundation

Music

• Joshua Bell, violinist
• Angela Brown, soprano opera singer at the Metropolitan Opera
• Hoagy Carmichael, songwriter and actor, author of the famous songs Stardust and Georgia on My Mind
• Booker T. Jones, songwriter, producer and frontman of the band Booker T. and the MGs
• John Cougar Mellencamp, musician
• Larry Ridley, jazz bassist and music educator
• Leonard Slatkin, composer and conductor of the BBC Symphony Orchestra until 2004

Politics

• Michael Badnarik, 2004 US Presidential candidate
• Evan Bayh, US Senator, former governor of Indiana
• LeRoy Edgar Burney, former Surgeon General of the United States
• Dan Coats, former US Senator, US ambassador to Germany
• Robert Gates, former CIA director and National Security Council member
• William E. Jenner, former US Senator
• Charles Peter Kennedy, British politician and Member of Parliament, leader of the British Liberal Democrat party
• Richard Monroe Miles, US ambassador to Georgia
• Frank O'Bannon, former governor of Indiana
• Newell Sanders, former US Senator
• Edgar Whitcomb, former governor of Indiana
• Wendell Willkie, 1940 Republican presidential candidate

Science and Technology

• Carl Otto Lampland, astronomer
• Wardell Pomeroy, sexologist
• Vesto Slipher, astronomer
• John T. Thompson, military officer, developer of the Springfield 1903 rifle, the M1911 pistol and inventor of the Thompson submachine gun
• Mansukh C. Wani, cancer researcher, discoverer of Taxol
• David Wolf, astronaut, space shuttle, Mir and ISS veteran
• James D. Watson, co-discoverer of DNA structure, author of The Double Helix, winner of the 1962 Nobel Prize in Physiology or Medicine

Sports

• Ted Kluszewski, Major League baseball player and coach
• Mark Spitz, Olympic gold medalist swimmer
• Isiah Thomas, former NBA star, Basketball Hall of Famer
• Sam Wyche, NFL player and coach