- Strom Thurmond, former U.S. Senator
- James F. Dickey,
Pulitzer Prize winning author
- Robert H. Brooks,
founder and president of Hooters
- Harvey Gantt, former mayor of Charlotte, NC and first African-American
graduate of Clemson University
- Jane Robelot, news anchor
- William "Refrigerator" Perry, former NFL
- Dwight Clark, former NFL player
- Gigi Fernandez, former women's tennis player
- Khalil Green, San Diego Padres baseball player
- Johnathan Byrd, PGA TOUR
- Shawn Crawford, 2004 Olympic gold and silver medalist in track and
- David Beasley, South Carolina governor (1995-1999)
- Mack Fleming, owner/operator
of only commercial tea plantation in the
- Leroy Hill,football star
- Bob Peeler, South Carolina
lieutenant governor (1995-2003)
- Horace Grant, NBA player
- Scott Lazar, first person to
free-climb Venezuela's Angel Falls.
- Nancy O'Dell, former Miss
South Carolina and host of "Access Hollywood"
- Chris Luca, Winner of Amazing Race
- Aaron Buerge, "The Bachelor,"
- James Michael Tyler, Gunther on "Friends"
- Joseph Blake
Mundy, Famous Political Activist