Array

• Otto Stern, Nobel Prize in Physics, 1943
• Herbert Simon, Bank of Sweden Prize in Economic Sciences, 1978
• Franco Modigliani, Bank of Sweden Prize in Economic Sciences, 1985
• Merton Miller, Bank of Sweden Prize in Economic Sciences, 1990
• John Forbes Nash, Bank of Sweden Prize in Economic Sciences, 1994 - the subject of A Beautiful Mind
• Robert Lucas Jr, Bank of Sweden Prize in Economic Sciences, 1995
• John A. Pople, Nobel Prize in Chemistry, 1998
• Finn E. Kydland, Bank of Sweden Prize in Economic Sciences, 2004
• Edward C. Prescott, Bank of Sweden Prize in Economic Sciences, 2004

Array

• Alan Perlis, compiler construction, 1966 - first Turing Award winner
• Allen Newell and Herbert Simon, artificial intelligence, 1975
• Dana S. Scott, nondeterministic machines, 1976
• Ivan Sutherland, computer graphics, 1998
• Edward Feigenbaum and Raj Reddy, artificial intelligence, 1993
• Manuel Blum, computational complexity theory, 1995

Science and Technology

• Paul Allaire, Xerox CEO
• Andy Bechtolsheim (M.S.), co-founder of Sun Microsystems
• Charles Geschke (Ph.D.), co-founder of Adobe Systems
• James Gosling (Ph.D.), creator of Java programming language
• David Kelley, founder of IDEO
• Vinod Khosla (M.S.), co-founder of Sun Microsystems
• Edgar Mitchell, astronaut (6th man to walk on the moon)
• John Ousterhout (Ph.D.), inventor of the Tcl scripting language
• Richard F. Rashid, computer scientist, Microsoft Research SVP
• Judith Resnik, astronaut who died in the Space Shuttle Challenger explosion during the launch of the mission STS-51-L.
• Avie Tevanian (Ph.D.), Apple CTO
• Stephanie L. Kwolek, inventor of Kevlar

Performing Arts, Movie, and Television

• René Auberjonois, actor
• Stephen Bochco, writer and producer for television shows, including NYPD Blue
• Ted Danson, actor, best known as "Sam", the Cheers bartender
• Barbara Feldon, actress, Get Smart
• Josh Groban, left after freshman year, pop star solo vocalist
• Mariette Hartley, actress
• Holly Hunter, Academy Award winning actress
• Jack Klugman, Emmy award winning actor
• David Lander, actor, best known for his portrayal of Squiggy on the sitcom Laverne and Shirley
• Judith Light, Daytime Emmy Award winning actress (best known for One Life to Live and Who's the Boss?)
• Keith Lockhart, conductor of the Boston Pops Orchestra
• Ming-Na, television and movie actress, winner of the Annie Award as the voice of "Mulan" in Mulan
• George Peppard, actor
• Billy Price, MaPW, blues singer
• George A. Romero, film director, best known for Night of the Living Dead and Dawn of the Dead (1978)
• Ann Roth, Academy Award-winning costumer designer
• Laura San Giacomo, actress
• Stephen Schwartz, broadway composer of shows including Wicked, Godspell and Pippin. Pippin, in fact, was originally a CMU production, presented by the Scotch'n'Soda theatrical club on campus under the title Pippin Pippin.
• Jack Smith (deceased), Emmy Award-winning correspondent with ABC News
• Blair Underwood, actor
• Dagmara Dominczyk, actress

Visual Arts

• Andy Warhol, American painter and major figure in the pop art movement.
• Mel Bochner, a pioneer of Post-Minimal arts and Conceptual art.
• Philip Pearlstein, American figure painter.
• Jonathan Borofsky, 20th-Century Conceptual artist and sculptor.
• John Currin, contemporary figure and portrait painter.

Literature

• Iris Dart, author of Beaches
• E. L. Konigsburg, author of children's books
• Astro Teller, author of Exegesis